RNU2-11P

Across TCGA pan-cancer cohorts, RNU2-11P RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RNU2-11P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU2-11P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU2-11P expression acts as an unfavorable survival marker, although some lineages such as BLCA and LUSC show a favorable association.

BLCA, COAD, and LUAD are the cancer types where RNU2-11P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.606	0.323	<.001	95	view →
COAD	OS	Tertile	All	0.796	0.952	<.001	71	view →
LUAD	OS	Quartile	II,III,IV	0.559	0.886	<.001	58	view →
LUSC	OS	Tertile	All	0.839	0.707	<.001	43	view →
UCS	OS	Tertile	II,III,IV	0.649	0.257	.006	34	view →
LIHC	OS	Tertile	All	0.697	0.846	<.001	33	view →
KIRC	DFS	Quartile	All	0.470	0.714	<.001	32	view →
PAAD	DFS	Quartile	II,III,IV	0.440	0.182	<.001	28	view →
READ	DFS	Quartile	II,III,IV	0.389	0.800	.013	22	view →
SKCM	OS	Median	All	0.836	0.733	.004	21	view →
THYM	DFS	Median	II,III,IV	0.949	0.511	.004	21	view →
KIRP	DFS	Quartile	All	0.530	0.801	.011	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RNU2-11P–BLCA (OS)

Open the BLCA breakdown →