RNU11-5P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU11-5P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU11-5P data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher RNU11-5P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU11-5P expression acts as an unfavorable survival marker.

READ, UCEC, and SKCM are the cancer types where RNU11-5P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
READOSTertileAll0.1660.830<.00190view →
UCECOSTertileII,III,IV0.2040.768.00372view →
SKCMDFSTertileAll0.0440.728<.00154view →
THCADFSTertileAll0.0620.811<.00145view →
LUSCOSTertileAll0.3400.677.02645view →
PAADDFSTertileII,III,IV0.1830.441.01936view →
LUADOSTertileIII,IV0.2280.677.01536view →
OVDFSTertileII,III,IV0.2530.542.00718view →
LGGOSTertileAll0.5890.898.00215view →
PCPGDFSTertileAll0.5350.935.0403view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration