RNU1-78P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU1-78P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU1-78P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU1-78P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU1-78P expression acts as an unfavorable survival marker, although some lineages such as STAD and HNSC show a favorable association.

UVM, PAAD, and THCA are the cancer types where RNU1-78P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMDFSTertileAll0.0320.762<.00190view →
PAADOSTertileAll0.1120.640.00472view →
THCAOSTertileIV0.5791.000<.00169view →
KICHOSTertileII,III,IV0.0700.828<.00163view →
UCECOSTertileIV0.3080.748.00930view →
ACCOSTertileAll0.1470.685.01827view →
STADDFSTertileIII,IV0.6040.277.01924view →
LGGOSTertileAll0.4890.891.0049view →
HNSCOSTertileII,III,IV0.6360.341.0229view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration