RNA, U1 small nuclear 73, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU1-73P profile across patient tissues and cancer cell-line models. RNU1-73P expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, RNU1-73P is differentially expressed in 5, with the highest sampling consensus in THCA. Additionally, RNU1-73P RNA expression shows 9,962 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight HNSC, THCA, and DLBC as cancer lineages where RNU1-73P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU1-73P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU1-73P survival associations across molecular data types. RNU1-73P RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU1-73P RNA expression–survival associations across cancer types. High RNU1-73P expression shows unfavorable associations in THYM, LUSC, THCA and DLBC, but favorable associations in HNSC and BRCA. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .009). Together, the overview and detailed table identify HNSC as the clearest survival context for RNU1-73P RNA expression.
This table summarizes RNU1-73P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNU1-73P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU1-73P shows lower tumor expression in THCA, KICH, PAAD, KIRP and LUSC. The THCA box plot shows higher RNU1-73P RNA expression in normal versus tumor tissue (log2 FC = −0.255, t-test p < 0.001).
This table shows molecular features associated with RNU1-73P in patient tissues and cancer cell lines. In patient samples, RNU1-73P shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set.
