Across TCGA pan-cancer cohorts, RNU1-65P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU1-65P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNU1-65P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU1-65P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH, UCEC, and LUSC are the cancer types where RNU1-65P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU1-65P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.925	<.001	7	view →
UCEC	All	All	+0.628	.030	6	view →
LUSC	All	All	+0.060	.012	2	view →
BRCA	All	All	+0.040	.045	2	view →
LUAD	All	All	+0.099	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU1-65P RNA expression & survival · all RNU1-65P data types