RNU1-57P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU1-57P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU1-57P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU1-57P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU1-57P expression acts as an unfavorable survival marker.

SKCM, KIRC, and BRCA are the cancer types where RNU1-57P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSTertileAll0.0290.738<.001108view →
KIRCDFSTertileIII,IV0.1270.749.00436view →
BRCADFSTertileAll0.6990.950.00136view →
GBMOSTertileAll0.0330.416<.00118view →
LIHCDFSTertileAll0.0920.543.01618view →
COADOSTertileIV0.1750.671.00318view →
BLCADFSTertileIII,IV0.1590.572.0369view →
LGGOSTertileAll0.3160.830.0169view →
LUADOSTertileAll0.2770.787.0229view →
READDFSTertileIV0.2550.628.0209view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration