Across TCGA pan-cancer cohorts, RNU1-52P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU1-52P data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RNU1-52P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU1-52P expression acts as an unfavorable survival marker.

LUSC, KIRC, and BRCA are the cancer types where RNU1-52P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	III,IV	0.057	0.691	<.001	72	view →
KIRC	DFS	Tertile	All	0.327	0.661	<.001	36	view →
BRCA	DFS	Tertile	II,III,IV	0.205	0.521	.018	36	view →
THCA	DFS	Tertile	All	0.158	0.820	.002	36	view →
LIHC	OS	Tertile	All	0.245	0.577	.010	12	view →
SARC	OS	Tertile	All	0.300	0.737	.002	12	view →
SKCM	OS	Tertile	IV	0.133	0.621	.019	9	view →
PCPG	DFS	Tertile	All	0.161	0.819	.004	9	view →
BLCA	DFS	Tertile	All	0.134	0.352	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration

Same gene, other analysis: RNU1-52P tumor-vs-normal RNA expression · all RNU1-52P data types