RNU1-138P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU1-138P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNU1-138P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU1-138P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU1-138P expression acts as an unfavorable survival marker, although some lineages such as ACC and THCA show a favorable association.

HNSC, BLCA, and KICH are the cancer types where RNU1-138P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSMedianIV0.4510.633<.001128view →
BLCAOSTertileAll0.4600.655<.001108view →
KICHDFSQuartileAll0.5600.942<.00187view →
MESOOSTertileAll0.3560.622<.00180view →
TGCTDFSTertileII,III,IV0.0150.919<.00148view →
LGGOSQuartileAll0.3460.482<.00137view →
SARCDFSTertileAll0.2440.457<.00130view →
COADOSTertileIV0.2410.714<.00118view →
PAADDFSTertileAll0.2400.430.04518view →
ACCOSQuartileIV0.9610.400.00615view →
GBMDFSMedianAll0.1740.379.0039view →
THCAOSTertileAll0.9950.959.0139view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

Exploration