RNU1-131P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU1-131P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU1-131P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU1-131P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU1-131P expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

BRCA, KIRC, and DLBC are the cancer types where RNU1-131P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCADFSTertileII,III,IV0.6080.892<.00172view →
KIRCDFSTertileAll0.2810.799.00157view →
DLBCDFSTertileII,III,IV0.4260.851.02345view →
BLCAOSTertileAll0.1880.618.01236view →
SKCMDFSTertileII,III,IV0.0580.708<.00118view →
OVOSTertileII,III,IV0.6310.706.0486view →
LUSCDFSTertileII,III,IV0.7720.339.0493view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU1-131P–BRCA (DFS)

Kaplan–Meier survival curve for RNU1-131P RNA-high vs -low samples in BRCA.

Open the BRCA breakdown →

Exploration