Across TCGA pan-cancer cohorts, RNU1-129P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNU1-129P’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RNU1-129P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU1-129P is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.
LIHC, STAD, and COAD are the cancer types where RNU1-129P tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU1-129P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.