RNU1-103P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU1-103P RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RNU1-103P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RNU1-103P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU1-103P is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

COAD, STAD, and BRCA are the cancer types where RNU1-103P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU1-103P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADMaleII,III,IV+0.982<.0016view →
STADMaleIV+0.425<.0014view →
BRCAAllAll−0.280.0064view →
CHOLAllAll+1.828<.0013view →
LUADAllAll+0.285.0293view →
LIHCAllAll+0.190.0203view →
LUSCAllAll+0.337.0212view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RNU1-103P–COAD

Tumor-vs-normal expression box plot for RNU1-103P RNA in COAD.

Open the COAD breakdown →

Exploration