RNPS1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNPS1 mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNPS1-associated genes across cancer lineages are MIR4752, MIR3938, and MIR502. Each is linked with RNPS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNPS1-to-partner and partner-to-RNPS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNPS1→partner) and Y-score (partner→RNPS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCMIR4752 →+0.489+6.936<.001<.00132
BLCAMIR3938 →+0.273+7.640<.001.00931
BLCAMIR502 →+0.312+7.640<.001.00931
BLCAMIR8069-2 →+0.313+7.640<.001.00931
COADRNU6-340P →+0.363+7.741<.001.00931
UCECMIR7702 →+0.415+5.253<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

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