RNPEPL1

Across TCGA pan-cancer cohorts, RNPEPL1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RNPEPL1 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RNPEPL1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RNPEPL1 expression acts as an unfavorable survival marker.

CCRCC, LSCC, and HNSC are the cancer types where RNPEPL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	II,III,IV	0.206	0.695	.026	12	view →
LSCC	OS	Median	II,III,IV	0.879	1.000	.020	7	view →
HNSC	DFS	Tertile	All	0.855	1.000	.020	4	view →
LUAD	DFS	Quartile	III,IV	0.334	0.787	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RNPEPL1–CCRCC (OS)

Open the CCRCC breakdown →