RNPEPL1

Across TCGA cell cohorts, RNPEPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,633 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible RNPEPL1-associated GO terms across cancer lineages are tRNA metabolic process, Transcription initiation at RNA polymerase III promoter, and Ribosomal small subunit biogenesis. Each is linked with RNPEPL1 in more than 13 cancer types. Because this analysis shows association rather than direction, both RNPEPL1-to-partner and partner-to-RNPEPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA metabolic process grouped by RNPEPL1-low versus RNPEPL1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNPEPL1→partner) and Y-score (partner→RNPEPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	tRNA metabolic process →	-0.046	-0.758	.001	.005	3	14
PANCREAS	Transcription initiation at RNA polymerase III promoter →	-0.109	-1.011	<.001	<.001	3	12
LIVER	Ribosomal small subunit biogenesis →	-0.087	-0.600	.001	.005	3	12
PANCREAS	Maturation of SSU-rRNA →	-0.121	-1.096	<.001	<.001	3	12
LIVER	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.142	-0.856	.002	.002	3	12
PANCREAS	DNA-templated transcription termination →	-0.115	-1.033	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,633 associations by consensus.

tRNA metabolic process by RNPEPL1 expression — SKIN

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