RNPEP

Across TCGA cell cohorts, RNPEP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,174 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RNPEP-associated GO terms across cancer lineages are Tricarboxylic acid cycle, Heme biosynthetic process, and Pyrimidine deoxyribonucleotide biosynthetic process. Each is linked with RNPEP in more than 9 cancer types. Because this analysis shows association rather than direction, both RNPEP-to-partner and partner-to-RNPEP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tricarboxylic acid cycle grouped by RNPEP-low versus RNPEP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNPEP→partner) and Y-score (partner→RNPEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Tricarboxylic acid cycle →	+0.103	+0.669	.002	.002	2	10
BLOOD_Lymphoma	Heme biosynthetic process →	+0.084	+1.070	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Pyrimidine deoxyribonucleotide biosynthetic process →	+0.140	+0.560	.004	.006	3	8
PANCREAS	Pigment biosynthetic process →	+0.065	+0.558	.003	<.001	3	8
BLOOD_Lymphoma	Tetrapyrrole biosynthetic process →	+0.097	+1.377	<.001	<.001	3	8
BLOOD_Lymphoma	Porphyrin-containing compound biosynthetic process →	+0.097	+1.377	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,174 associations by consensus.

Tricarboxylic acid cycle by RNPEP expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →