Across TCGA patient cohorts, RNPC3 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNPC3-associated genes across cancer lineages are 14-3-3_beta, JNK2, and MEK1. Each is linked with RNPC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNPC3-to-partner and partner-to-RNPC3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNPC3→partner) and Y-score (partner→RNPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.164	-3.673	<.001	.001	3	1
UCEC	JNK2 →	+0.235	+3.179	.006	.010	3	1
UCEC	MEK1 →	+0.570	+3.906	<.001	<.001	3	1
UCEC	p27_pT157 →	-0.074	-2.115	.003	.019	3	1
UCEC	p62 Lck ligand →	+0.324	+3.179	.022	.010	3	1
UCEC	Caspase-7-cleavedD198 →	+0.783	+2.189	.002	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

RNPC3 survival (RNA) · tumor vs normal (RNA) · all RNPC3 data types