RNMT

Across TCGA patient cohorts, RNMT protein abundance is significantly associated with the RNA expression of many other genes, with 17,032 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNMT-associated genes across cancer lineages are SEH1L, CEP76, and AFG3L2. Each is linked with RNMT in more than 9 cancer types. Because this analysis shows association rather than direction, both RNMT-to-partner and partner-to-RNMT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNMT versus SEH1L in LSCC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNMT→partner) and Y-score (partner→RNMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SEH1L →	+0.800	+0.520	<.001	<.001	3	10
LSCC	CEP76 →	+0.889	+0.560	<.001	<.001	3	9
HNSC	AFG3L2 →	+0.775	+0.374	<.001	<.001	3	9
HNSC	PTPN2 →	+0.590	+0.372	<.001	<.001	3	9
LSCC	FAM210A →	+0.738	+0.508	<.001	<.001	3	9
LSCC	CEP192 →	+0.723	+0.496	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,032 associations by consensus.

RNMT vs SEH1L — LSCC

Explore this scatter interactively →