RNMT

Across TCGA cell cohorts, RNMT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,727 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNMT-associated GO terms across cancer lineages are RNA (guanine-N7)-methylation, mRNA transport, and RNA export from nucleus. Each is linked with RNMT in more than 17 cancer types. Because this analysis shows association rather than direction, both RNMT-to-partner and partner-to-RNMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA (guanine-N7)-methylation grouped by RNMT-low versus RNMT-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNMT→partner) and Y-score (partner→RNMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RNA (guanine-N7)-methylation →	+0.142	+0.942	<.001	<.001	3	18
STOMACH	mRNA transport →	+0.140	+0.983	<.001	<.001	3	12
BONE	RNA export from nucleus →	+0.124	+0.780	<.001	<.001	3	12
BONE	mRNA export from nucleus →	+0.120	+0.901	.001	<.001	3	12
OESOPHAGUS	Negative regulation of macrophage colony-stimulating factor signaling pathway →	+0.258	+1.190	<.001	<.001	3	12
PANCREAS	Regulation of androgen receptor signaling pathway →	+0.077	+0.813	.004	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,727 associations by consensus.

RNA (guanine-N7)-methylation by RNMT expression — BONE

Explore this box plot interactively →