Across TCGA patient cohorts, RNLS RNA expression is significantly associated with the protein abundance of many other proteins, with 12,938 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNLS-associated proteins across cancer lineages are PTEN, SSRP1, and DDAH2. Each is linked with RNLS in more than 5 cancer types. Because this analysis shows association rather than direction, both RNLS-to-partner and partner-to-RNLS results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNLS→partner) and Y-score (partner→RNLS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTEN →	+0.264	+0.293	.001	.007	3	6
GBM	SSRP1 →	-0.384	-0.449	<.001	<.001	3	4
LSCC	DDAH2 →	+0.370	+0.510	.002	<.001	3	4
GBM	DNMT1 →	-0.472	-0.643	<.001	<.001	3	4
BRCA	PSAT1 →	-1.076	-0.463	<.001	.007	3	4
GBM	SUZ12 →	-0.306	-0.438	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,938 associations by consensus.

Exploration

RNLS survival (RNA) · tumor vs normal (RNA) · all RNLS data types