Across TCGA patient cohorts, RNLS protein abundance is significantly associated with the RNA expression of many other genes, with 9,651 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNLS-associated genes across cancer lineages are EME1, NCAPH, and ALDH2. Each is linked with RNLS in more than 5 cancer types. Because this analysis shows association rather than direction, both RNLS-to-partner and partner-to-RNLS results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNLS→partner) and Y-score (partner→RNLS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EME1 →	-0.697	-0.409	.001	.004	3	6
LUAD	NCAPH →	-0.773	-0.351	<.001	<.001	3	5
BRCA	ALDH2 →	+0.815	+0.374	.001	.002	3	5
BRCA	AOX1 →	+1.172	+0.400	<.001	.002	3	5
CCRCC	ACSM5 →	+0.964	+0.294	<.001	.005	3	5
UCEC	F10 →	+0.848	+0.445	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,651 associations by consensus.

Exploration

RNLS survival (RNA) · tumor vs normal (RNA) · all RNLS data types