Across TCGA cell cohorts, RNLS mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNLS-associated genes across cancer lineages are METTL21C and C6orf118. Each is linked with RNLS in more than 1 cancer types. Because this analysis shows association rather than direction, both RNLS-to-partner and partner-to-RNLS results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNLS→partner) and Y-score (partner→RNLS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	METTL21C →	+0.055	+4.133	<.001	.003	3	1
LARGE_INTESTINE	C6orf118 →	+0.108	+3.793	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

RNLS survival (RNA) · tumor vs normal (RNA) · all RNLS data types