RNGTT

Across TCGA pan-cancer cohorts, RNGTT mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RNGTT data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RNGTT mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RNGTT expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, PDAC, and UCEC are the cancer types where RNGTT mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	0.951	0.636	.001	23	view →
PDAC	OS	Median	II,III,IV	0.412	0.569	.025	14	view →
UCEC	OS	Median	All	0.914	0.982	.033	4	view →
CCRCC	OS	Median	IV	1.000	0.202	.034	4	view →
LUAD	DFS	Tertile	All	0.852	0.506	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RNGTT–LSCC (OS)

Open the LSCC breakdown →