RNGTT

Across TCGA cell cohorts, RNGTT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,992 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNGTT-associated GO terms across cancer lineages are 7-methylguanosine RNA capping, 7-methylguanosine mRNA capping, and Regulation of chromosome condensation. Each is linked with RNGTT in more than 19 cancer types. Because this analysis shows association rather than direction, both RNGTT-to-partner and partner-to-RNGTT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 7-methylguanosine RNA capping grouped by RNGTT-low versus RNGTT-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNGTT→partner) and Y-score (partner→RNGTT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	7-methylguanosine RNA capping →	+0.139	+1.222	<.001	<.001	3	20
OESOPHAGUS	7-methylguanosine mRNA capping →	+0.139	+1.222	<.001	<.001	3	20
OVARY	Regulation of chromosome condensation →	+0.182	+0.815	<.001	<.001	3	19
KIDNEY	Mitotic spindle assembly →	+0.122	+1.008	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic sister chromatid separation →	+0.144	+0.851	.003	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of metaphase/anaphase transition of cell cycle →	+0.129	+0.919	.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,992 associations by consensus.

7-methylguanosine RNA capping by RNGTT expression — OESOPHAGUS

Explore this box plot interactively →