RNFT2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNFT2 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RNFT2 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNFT2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RNFT2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

UCEC and GBM are the cancer types where RNFT2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSTertileIII,IV1.0000.293.01616view →
GBMDFSQuartileAll0.5050.293.0092view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RNFT2–UCEC (OS)

Kaplan–Meier survival curve for RNFT2 mass-spec protein-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration