Across TCGA patient cohorts, RNFT1 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNFT1-associated genes across cancer lineages are ATM, EGFR_pY1068, and eIF4E. Each is linked with RNFT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNFT1-to-partner and partner-to-RNFT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNFT1→partner) and Y-score (partner→RNFT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.521	-3.700	.013	.001	3	2
UCEC	EGFR_pY1068 →	-0.291	-3.459	.012	.005	3	1
UCEC	eIF4E →	+0.194	+3.000	.048	.036	3	1
UCEC	ERK2 →	+0.212	+2.321	.018	.034	3	1
UCEC	JNK2 →	+0.373	+2.584	<.001	.011	3	1
UCEC	PCNA →	+0.263	+3.459	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

RNFT1 survival (RNA) · tumor vs normal (RNA) · all RNFT1 data types