RNF7

Across TCGA cell cohorts, RNF7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,318 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RNF7-associated GO terms across cancer lineages are Regulation of cardiolipin metabolic process, Positive regulation of protein ubiquitination, and Regulation of cap-independent translational initiation. Each is linked with RNF7 in more than 8 cancer types. Because this analysis shows association rather than direction, both RNF7-to-partner and partner-to-RNF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cardiolipin metabolic process grouped by RNF7-low versus RNF7-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF7→partner) and Y-score (partner→RNF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of cardiolipin metabolic process →	+0.124	+0.493	<.001	<.001	3	9
SOFT_TISSUE	Positive regulation of protein ubiquitination →	+0.073	+0.674	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Regulation of cap-independent translational initiation →	+0.136	+0.818	.008	.007	2	9
LUNG_NSCLC_LUSC	Positive regulation of cap-independent translational initiation →	+0.136	+0.818	.008	.007	2	9
LARGE_INTESTINE	Pteridine-containing compound catabolic process →	+0.132	+0.424	<.001	<.001	3	7
SOFT_TISSUE	De novo centriole assembly →	-0.140	-0.670	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,318 associations by consensus.

Regulation of cardiolipin metabolic process by RNF7 expression — SKIN

Explore this box plot interactively →