Across TCGA patient cohorts, RNF5 protein abundance is significantly associated with the RNA expression of many other genes, with 12,504 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNF5-associated genes across cancer lineages are AGPAT1, CUTA, and RPS10. Each is linked with RNF5 in more than 7 cancer types. Because this analysis shows association rather than direction, both RNF5-to-partner and partner-to-RNF5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF5→partner) and Y-score (partner→RNF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AGPAT1 →	+0.503	+0.295	.004	.001	3	8
OV	CUTA →	+0.550	+0.838	<.001	<.001	3	7
HNSC	RPS10 →	+0.600	+0.436	<.001	<.001	3	6
HNSC	ATAT1 →	+0.563	+0.300	.002	<.001	3	6
HNSC	DCAF16 →	+0.634	+0.242	<.001	<.001	3	6
HNSC	CSNK2B →	+0.632	+0.461	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,504 associations by consensus.

Exploration

RNF5 survival (RNA) · tumor vs normal (RNA) · all RNF5 data types