Across TCGA patient cohorts, RNF5 mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF5-associated genes across cancer lineages are TPT1P11, RN7SL254P, and RNU6-328P. Each is linked with RNF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF5-to-partner and partner-to-RNF5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF5→partner) and Y-score (partner→RNF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TPT1P11 →	+0.083	+5.418	<.001	.005	3	2
BLCA	RN7SL254P →	+0.152	+4.685	<.001	.007	3	2
UCEC	RNU6-328P →	+0.386	+3.097	.002	.004	3	2
UCEC	RNA5SP534 →	+0.519	+3.242	<.001	.007	3	1
CESC	RN7SL62P →	+0.139	+5.812	<.001	.003	3	1
CESC	RN7SL415P →	+0.143	+5.812	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

RNF5 survival (RNA) · tumor vs normal (RNA) · all RNF5 data types