Across TCGA cell cohorts, RNF5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,756 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RNF5-associated GO terms across cancer lineages are Positive regulation of developmental pigmentation, Protein peptidyl-prolyl isomerization, and Regulation of pigment cell differentiation. Each is linked with RNF5 in more than 9 cancer types. Because this analysis shows association rather than direction, both RNF5-to-partner and partner-to-RNF5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF5→partner) and Y-score (partner→RNF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of developmental pigmentation →	+0.124	+0.923	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein peptidyl-prolyl isomerization →	+0.094	+0.763	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Regulation of pigment cell differentiation →	+0.133	+0.710	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Positive regulation of pigment cell differentiation →	+0.133	+0.710	<.001	<.001	3	8
BONE	Synaptic vesicle cytoskeletal transport →	+0.075	+0.551	<.001	.005	3	8
BONE	Synaptic vesicle transport along microtubule →	+0.075	+0.551	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,756 associations by consensus.

Exploration

RNF5 survival (RNA) · tumor vs normal (RNA) · all RNF5 data types