RNF44

Across TCGA cell cohorts, RNF44 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,925 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RNF44-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Transcription pausing by RNA polymerase II, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with RNF44 in more than 15 cancer types. Because this analysis shows association rather than direction, both RNF44-to-partner and partner-to-RNF44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by RNF44-low versus RNF44-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF44→partner) and Y-score (partner→RNF44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.229	+1.507	<.001	<.001	3	16
BONE	Transcription pausing by RNA polymerase II →	+0.155	+1.268	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.092	+0.939	<.001	<.001	3	15
STOMACH	RNA catabolic process →	+0.073	+1.524	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.104	+1.036	<.001	<.001	3	15
BONE	Negative regulation of translational initiation →	+0.115	+1.283	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,925 associations by consensus.

Pre-mRNA catabolic process by RNF44 expression — BONE

Explore this box plot interactively →