Across TCGA patient cohorts, RNF39 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,254 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNF39-associated proteins across cancer lineages are PKP3, PPL, and MVB12A. Each is linked with RNF39 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNF39-to-partner and partner-to-RNF39 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF39→partner) and Y-score (partner→RNF39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PKP3 →	+0.884	+0.897	<.001	<.001	3	5
UCEC	PPL →	+0.783	+0.785	<.001	<.001	3	5
PDAC	MVB12A →	+0.270	+0.611	.003	.004	3	4
UCEC	PKN1 →	-0.314	-0.644	<.001	.006	3	4
HNSC	POF1B_S123 →	+1.292	+1.191	<.001	<.001	3	4
HNSC	NIBAN2 →	+0.452	+1.019	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,254 associations by consensus.

Exploration

RNF39 survival (RNA) · tumor vs normal (RNA) · all RNF39 data types