Across TCGA patient cohorts, RNF39 protein abundance is significantly associated with the RNA expression of many other genes, with 2,390 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNF39-associated genes across cancer lineages are PDE3B, AGT, and ABCB9. Each is linked with RNF39 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF39-to-partner and partner-to-RNF39 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF39→partner) and Y-score (partner→RNF39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDE3B →	-1.240	-1.251	.008	.005	3	2
BRCA	AGT →	-3.006	-0.767	.009	.002	3	2
BRCA	ABCB9 →	-0.702	-0.689	.004	.001	3	2
LUAD	POLR3K →	-0.575	-0.797	.003	.001	3	2
BRCA	TEDC2 →	-1.063	-0.766	.008	<.001	3	2
BRCA	NIPAL1 →	+1.133	+0.904	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,390 associations by consensus.

Exploration

RNF39 survival (RNA) · tumor vs normal (RNA) · all RNF39 data types