Across TCGA patient cohorts, RNF39 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF39-associated genes across cancer lineages are CD4+ memory T-cells, pro B-cells, and DC. Each is linked with RNF39 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF39-to-partner and partner-to-RNF39 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF39→partner) and Y-score (partner→RNF39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD4+ memory T-cells →	+0.013	+2.543	.042	.035	3	2
UCEC	pro B-cells →	+0.150	+2.823	.016	.036	3	2
COAD	DC →	+0.047	+2.833	<.001	.014	3	1
UCEC	MSC →	+0.263	+3.000	.029	.037	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

RNF39 survival (RNA) · tumor vs normal (RNA) · all RNF39 data types