Across TCGA cell cohorts, RNF39 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF39-associated genes across cancer lineages are DYNAP, SCGB3A2, and PFN3. Each is linked with RNF39 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF39-to-partner and partner-to-RNF39 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF39→partner) and Y-score (partner→RNF39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	DYNAP →	+0.119	+4.129	<.001	.007	3	1
LARGE_INTESTINE	SCGB3A2 →	+0.394	+4.095	<.001	.009	3	1
LARGE_INTESTINE	PFN3 →	+0.169	+4.467	<.001	.004	3	1
LARGE_INTESTINE	BTNL2 →	+0.081	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR2B3 →	+0.017	+4.415	<.001	.007	3	1
LARGE_INTESTINE	POTEB2 →	+0.009	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

RNF39 survival (RNA) · tumor vs normal (RNA) · all RNF39 data types