RNF38

Across TCGA patient cohorts, RNF38 protein abundance is significantly associated with the RNA expression of many other genes, with 3,668 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNF38-associated genes across cancer lineages are IL11RA, CEP85L, and SARDH. Each is linked with RNF38 in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF38-to-partner and partner-to-RNF38 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF38 versus IL11RA in UCEC, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF38→partner) and Y-score (partner→RNF38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IL11RA →	-0.718	-0.524	.006	<.001	3	3
UCEC	CEP85L →	-0.707	-0.471	.004	<.001	3	2
UCEC	SARDH →	-1.093	-0.444	.007	.002	3	2
HNSC	QRICH2 →	-0.785	-0.394	.004	.007	3	2
UCEC	LEF1 →	-2.091	-0.515	.003	.002	3	2
UCEC	ADAMTS18 →	-1.471	-0.491	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,668 associations by consensus.

RNF38 vs IL11RA — UCEC

Explore this scatter interactively →