RNF38

Across TCGA cell cohorts, RNF38 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,246 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF38-associated GO terms across cancer lineages are Stress granule assembly, RNA destabilization, and Regulation of mRNA catabolic process. Each is linked with RNF38 in more than 14 cancer types. Because this analysis shows association rather than direction, both RNF38-to-partner and partner-to-RNF38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Stress granule assembly grouped by RNF38-low versus RNF38-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF38→partner) and Y-score (partner→RNF38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Stress granule assembly →	+0.172	+0.707	<.001	.007	2	15
OVARY	RNA destabilization →	+0.069	+0.965	<.001	<.001	3	14
OVARY	Regulation of mRNA catabolic process →	+0.062	+0.891	<.001	<.001	3	14
BREAST	Positive regulation of myoblast differentiation →	+0.121	+0.912	<.001	.001	3	14
LUNG_SCLC	Peptidyl-serine phosphorylation →	+0.092	+0.907	<.001	<.001	3	13
LUNG_SCLC	Peptidyl-serine modification →	+0.092	+0.907	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,246 associations by consensus.

Stress granule assembly by RNF38 expression — STOMACH

Explore this box plot interactively →