RNF32

Across TCGA patient cohorts, RNF32 mutation is significantly associated with the RNA expression of many other genes, with 1,971 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF32-associated genes across cancer lineages are RN7SL656P, CDK8P1, and CDY3P. Each is linked with RNF32 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF32-to-partner and partner-to-RNF32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL656P grouped by RNF32-low versus RNF32-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF32→partner) and Y-score (partner→RNF32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL656P →	+0.043	+3.897	<.001	.009	3	2
COAD	CDK8P1 →	+0.456	+4.611	<.001	.004	3	2
READ	CDY3P →	+0.050	+7.276	<.001	<.001	3	2
READ	CYCSP22 →	+0.206	+5.421	<.001	.005	3	2
READ	FAM230J →	+0.026	+6.257	<.001	.001	3	2
UCEC	CCDC174 →	+0.271	+1.551	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,971 associations by consensus.

RN7SL656P by RNF32 expression — SKCM

Explore this box plot interactively →