RNF32-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNF32-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RNF32-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNF32-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNF32-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and OV show a favorable association.

KIRC, ACC, and UCEC are the cancer types where RNF32-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSMedianAll0.5460.687<.001161view →
ACCOSMedianAll0.3760.851.00149view →
UCECDFSMedianIII,IV0.7340.849.00640view →
KICHDFSQuartileAll0.5700.940.01031view →
LIHCOSQuartileAll0.6140.847<.00128view →
LGGDFSTertileAll0.6330.790<.00125view →
BRCAOSTertileIV0.8410.311.00620view →
OVOSMedianAll0.7300.650.00716view →
CESCDFSTertileIV0.6230.101.03914view →
HNSCOSQuartileII,III,IV0.4630.419.01413view →
PRADDFSTertileAll0.7390.926<.00112view →
READOSMedianIII,IV0.6770.276.01210view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration