RNF26

Across TCGA pan-cancer cohorts, RNF26 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RNF26 data layer compared with 30 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNF26 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RNF26 expression acts as an unfavorable survival marker.

KIRC, LIHC, and STAD are the cancer types where RNF26 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.054	0.881	<.001	48	view →
LIHC	DFS	Median	All	0.032	0.556	<.001	18	view →
STAD	OS	Median	II,III,IV	0.183	0.660	.009	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RNF26–KIRC (OS)

Open the KIRC breakdown →