RNF26

Across TCGA cell cohorts, RNF26 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,266 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF26-associated GO terms across cancer lineages are Spindle midzone assembly, Mitotic spindle elongation, and Mitotic spindle midzone assembly. Each is linked with RNF26 in more than 18 cancer types. Because this analysis shows association rather than direction, both RNF26-to-partner and partner-to-RNF26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle midzone assembly grouped by RNF26-low versus RNF26-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF26→partner) and Y-score (partner→RNF26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Spindle midzone assembly →	+0.236	+1.047	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Mitotic spindle elongation →	+0.292	+1.104	.003	.006	3	18
LUNG_NSCLC_LUSC	Mitotic spindle midzone assembly →	+0.292	+1.104	.003	.006	3	18
SOFT_TISSUE	Meiotic sister chromatid cohesion, centromeric →	+0.166	+1.068	<.001	<.001	3	18
STOMACH	Mitotic sister chromatid segregation →	+0.131	+0.925	<.001	<.001	3	17
STOMACH	Establishment of mitotic spindle localization →	+0.143	+0.921	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,266 associations by consensus.

Spindle midzone assembly by RNF26 expression — PANCREAS

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