RNF26

Across TCGA cell cohorts, RNF26 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF26-associated genes across cancer lineages are OR10T2, OR10R2, and OR4F15. Each is linked with RNF26 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF26-to-partner and partner-to-RNF26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10T2 grouped by RNF26-low versus RNF26-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF26→partner) and Y-score (partner→RNF26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR10T2 →	+0.275	+4.044	<.001	.009	3	2
LUNG_SCLC	OR10R2 →	+1.636	+4.269	<.001	.005	3	2
BLOOD_Leukemia	OR4F15 →	+0.006	+5.201	<.001	.006	3	2
LUNG_SCLC	CD1B →	+0.360	+4.523	<.001	.003	3	1
LUNG_SCLC	OR10K2 →	+0.020	+4.643	<.001	.004	3	1
LUNG_SCLC	PRAMEF10 →	+0.885	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

OR10T2 by RNF26 expression — LUNG_SCLC

Explore this box plot interactively →