Across TCGA patient cohorts, RNF222 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,618 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNF222-associated proteins across cancer lineages are FNDC3B, GRHL1, and GALNT7. Each is linked with RNF222 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNF222-to-partner and partner-to-RNF222 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF222→partner) and Y-score (partner→RNF222) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FNDC3B →	-0.399	-0.396	<.001	<.001	3	4
BRCA	GRHL1 →	+0.448	+0.322	<.001	<.001	3	4
BRCA	GALNT7 →	-0.531	-0.275	.001	<.001	3	4
LSCC	VASP →	-0.351	-0.561	<.001	<.001	3	4
UCEC	TRIM29 →	+1.348	+0.551	<.001	.001	3	4
UCEC	PKP1_S237 →	+1.564	+0.674	.008	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,618 associations by consensus.

Exploration

RNF222 survival (RNA) · tumor vs normal (RNA) · all RNF222 data types