Across TCGA patient cohorts, RNF222 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF222-associated genes across cancer lineages are MIR513B, RNA5SP424, and C1QBPP1. Each is linked with RNF222 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF222-to-partner and partner-to-RNF222 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF222→partner) and Y-score (partner→RNF222) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR513B →	+0.826	+5.621	<.001	.004	3	1
UCEC	RNA5SP424 →	+0.660	+5.242	<.001	.007	3	1
UCEC	C1QBPP1 →	+0.151	+5.621	<.001	.004	3	1
UCEC	TYMSP1 →	+0.118	+5.420	.001	.005	3	1
UCEC	RN7SKP232 →	+0.315	+5.133	<.001	.008	3	1
UCEC	IGLVI-68 →	+0.289	+5.852	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

RNF222 survival (RNA) · tumor vs normal (RNA) · all RNF222 data types