Across TCGA patient cohorts, RNF220 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF220-associated genes across cancer lineages are XRCC1, eEF2, and EGFR_pY1068. Each is linked with RNF220 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF220-to-partner and partner-to-RNF220 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF220→partner) and Y-score (partner→RNF220) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	XRCC1 →	+0.164	+2.815	.017	.036	3	2
UCEC	eEF2 →	+0.364	+1.459	.001	.012	3	2
UCEC	EGFR_pY1068 →	-0.259	-2.584	.001	.001	3	2
UCEC	GAPDH →	+0.377	+2.115	.030	.016	3	2
UCEC	JNK_pT183_Y185 →	-0.148	-1.678	.006	.019	3	2
UCEC	mTOR_pS2448 →	-0.116	-1.565	.016	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

RNF220 survival (RNA) · tumor vs normal (RNA) · all RNF220 data types