Across TCGA cell cohorts, RNF220 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,696 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RNF220-associated GO terms across cancer lineages are mRNA alternative polyadenylation, Regulation of metaphase plate congression, and Regulation of protein sumoylation. Each is linked with RNF220 in more than 13 cancer types. Because this analysis shows association rather than direction, both RNF220-to-partner and partner-to-RNF220 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF220→partner) and Y-score (partner→RNF220) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	mRNA alternative polyadenylation →	+0.096	+0.976	.001	<.001	3	14
BONE	Regulation of metaphase plate congression →	+0.208	+0.688	.005	.005	3	13
URINARY_TRACT	Regulation of protein sumoylation →	+0.101	+0.910	.003	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.063	+0.688	.001	.003	3	13
PANCREAS	Negative regulation of transcription initiation by RNA polymerase II →	+0.144	+0.827	<.001	<.001	3	13
BONE	RISC complex assembly →	+0.118	+0.686	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,696 associations by consensus.

Exploration

RNF220 survival (RNA) · tumor vs normal (RNA) · all RNF220 data types