Across TCGA cell cohorts, RNF220 mutation is significantly associated with the RNA expression of many other genes, with 181 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF220-associated genes across cancer lineages are PRRT1B, EIF3L, and CHMP4B. Each is linked with RNF220 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF220-to-partner and partner-to-RNF220 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF220→partner) and Y-score (partner→RNF220) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PRRT1B →	+0.032	+4.054	.001	.004	3	1
LARGE_INTESTINE	EIF3L →	+0.541	+3.237	.001	.003	3	1
LARGE_INTESTINE	CHMP4B →	-0.660	-3.416	.001	.002	3	1
LARGE_INTESTINE	RBFA →	+0.836	+3.502	<.001	.001	3	1
LARGE_INTESTINE	B9D1 →	+0.704	+2.451	.002	.009	3	1
LARGE_INTESTINE	PCCB →	+0.499	+3.295	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 181 associations by consensus.

Exploration

RNF220 survival (RNA) · tumor vs normal (RNA) · all RNF220 data types