RNF213

Across TCGA patient cohorts, RNF213 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,909 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RNF213-associated proteins across cancer lineages are TYMP, STAT1, and STAT2. Each is linked with RNF213 in more than 8 cancer types. Because this analysis shows association rather than direction, both RNF213-to-partner and partner-to-RNF213 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF213 versus TYMP in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF213→partner) and Y-score (partner→RNF213) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TYMP →	+0.873	+0.522	<.001	<.001	3	9
UCEC	STAT1 →	+0.704	+0.857	<.001	<.001	3	9
HNSC	STAT2 →	+0.414	+0.629	<.001	<.001	3	9
GBM	DDX58 →	+0.766	+0.573	<.001	<.001	3	8
BRCA	HELZ2 →	+0.472	+0.666	<.001	<.001	3	8
HNSC	CMPK2 →	+0.736	+0.838	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,909 associations by consensus.

RNF213 vs TYMP — GBM

Explore this scatter interactively →