Across TCGA pan-cancer cohorts, RNF212 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RNF212 data layer compared with 20 for mass-spec protein.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNF212 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RNF212 expression acts as an unfavorable survival marker.
UCEC are the cancer types where RNF212 Mutation most reproducibly stratifies survival.