RNF212

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNF212 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RNF212 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNF212 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RNF212 expression acts as an unfavorable survival marker.

UCEC are the cancer types where RNF212 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianIV0.2310.592.0366view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

RNF212–UCEC (OS)

Kaplan–Meier survival curve for RNF212 mutant vs wild-type samples in UCEC.

Open the UCEC breakdown →

Exploration