Across TCGA patient cohorts, RNF208 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,083 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNF208-associated proteins across cancer lineages are RIC1_S1037, HSPE1, and SSH1_S576. Each is linked with RNF208 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNF208-to-partner and partner-to-RNF208 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF208→partner) and Y-score (partner→RNF208) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RIC1_S1037 →	-0.541	-0.708	<.001	<.001	3	5
HNSC	HSPE1 →	+0.435	+0.651	.003	<.001	3	5
GBM	SSH1_S576 →	-0.600	-0.573	.006	.002	3	5
LSCC	STRBP →	+0.760	+0.591	<.001	<.001	3	5
LSCC	TBC1D2B →	-0.355	-0.614	<.001	<.001	3	5
LSCC	VASP →	-0.377	-0.588	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,083 associations by consensus.

Exploration

RNF208 survival (RNA) · tumor vs normal (RNA) · all RNF208 data types