Across TCGA cell cohorts, RNF208 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,836 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RNF208-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with RNF208 in more than 12 cancer types. Because this analysis shows association rather than direction, both RNF208-to-partner and partner-to-RNF208 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF208→partner) and Y-score (partner→RNF208) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of myoblast fusion →	+0.076	+1.408	.001	.001	3	13
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.101	+1.184	<.001	.003	3	11
OVARY	Negative regulation of myoblast fusion →	+0.104	+1.450	.001	.001	3	10
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.107	+1.297	<.001	.001	3	10
LUNG_SCLC	Transcription pausing by RNA polymerase II →	+0.135	+1.249	<.001	<.001	3	9
OESOPHAGUS	Establishment of epithelial cell apical/basal polarity →	-0.183	-1.495	.004	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,836 associations by consensus.

Exploration

RNF208 survival (RNA) · tumor vs normal (RNA) · all RNF208 data types